Journal Information
Vol. 98. Issue 5.
Pages 347-350 (June - July 2007)
Vol. 98. Issue 5.
Pages 347-350 (June - July 2007)
Case reports
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Acquired Lymphangiectases and Breast Cancer
Linfangiectasias Adquiridas y Cáncer de Mama
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F. Valdésa,
Corresponding author
Fernando.Valdes.Tascon@sergas.es

Correspondence: Unidad de Dermatología. Hospital da Costa. Rafael Vior s/n. 27880 Burela. Lugo. Spain.
, C. Peteirob, J. Toribiob
a Unidad de Dermatología, Hospital da Costa, Burela, Lugo, Spain
b Servicio de Dermatología, Hospital Clínico Universitario-Hospital Gil Casares, Facultad de Medicina, Santiago de Compostela, La Coruña, Spain
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Abstract

Acquired lymphangiectases represent superficial lymphatic dilatations caused by a wide range of processes. Many cases reported in the literature develop in patients with upper limb lymphedema secondary to mastectomy, radiotherapy, keloids or scleroderma. Clinically they consist of translucent vesicles in a chronic lymphedematous area. Histologically they are characterized by the presence of dilated spaces with flattened endothelial cells in the papillary dermis. All these cases have a good prognosis and there have not been any reports of malignant transformation. We describe a 67-year-old woman that showed multiple papules along her left upper limb associated with lymphedema. She had undergone a mastectomy followed by radiotherapy fourteen years before due to a breast cancer. Laboratory and radiological exams were within normal limits. The cutaneous lesions showed characteristic clinical and histological features of lymphangiectases and they progressively resolve in several weeks without any treatment.

Key words:
Lymphangiectases
Lymphangioma
Breast tumors
Resumen

Las linfangiectasias adquiridas son dilataciones de los pasos linfáticos superficiales producidas por una gran variedad de procesos. Muchos casos se recogen en la literatura en pacientes con linfedemas en extremidades superiores como complicaciones de mastectomía, radioterapia, queloides o esclerodermia. Clínicamente presentan vesículas traslúcidas sobre una zona de linfedema crónico. A nivel histopatológico, se caracterizan por la presencia de espacios dilatados en la dermis papilar con células endoteliales aplanadas. Todos estos casos tienen buen pronóstico y no se han descrito transformaciones hacia la malignidad. Recogemos el caso de una paciente de 67 años de edad que presentaba múltiples pápulas a lo largo de su extremidad superior izquierda asociadas a linfedema. Catorce años atrás había sufrido una mastectomía y posterior tratamiento radioterápico a causa de un cáncer de mama. Los estudios analíticos y las exploraciones radiológicas se encontraban dentro de la normalidad. Las lesiones cutáneas mostraban las características clínicas y patológicas que caracterizan a las linfangiectasias cutáneas y se resolvieron progresivamente en varias semanas sin ningún tratamiento.

Palabras clave:
linfangiectasias
linfangioma
tumores de mama
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References
[1.]
S.E. Moon, J.I. Youn, Y.S. Lee.
Acquired cutaneous lymphangiectasia.
Br J Dermatol, 129 (1993), pp. 193-195
[2.]
C. Díaz-Cascajo, S. Borghi, W. Weyers, H. Retzlaff, L. Requena, D. Metze, et al.
Benign lymphangiomatous papules of the skin following radiotherapy: a case report of five new cases and review of the literature.
Histopathology, 35 (1999), pp. 319-327
[3.]
C. Serra, E. Nagore, A. Alfaro, S. Almenar, C. Requena, O. Sanmartín, et al.
Pápulas linfangiomatosas benignas secundarias al tratamiento de cáncer de mama.
Actas Dermosifiliogr, 95 (2004), pp. 501-503
[4.]
R.B. Mallett, G.K. Curley, P.S. Mortimer.
Acquired lymphangioma: report of four cases and a discussion of the pathogenesis.
Br J Dermatol, 126 (1992), pp. 380-382
[5.]
H. Plotnick, D. Richfield.
Tuberous lymphangiectatic varices secondary to radical mastectomy.
AMA Arch Derm, 74 (1956), pp. 466-468
[6.]
V. Giannelli, P.F. Rockley.
Acquired lymphangiectasis following mastectomy and radiation therapy-report of a case and review of the literature.
Cutis, 58 (1996), pp. 276-278
[7.]
B. Leshin, D.C. Whitaker, E. Foucar.
Lymphangioma circumscriptum following mastectomy and radiation therapy.
J Am Acad Dermatol, 15 (1986), pp. 1117-1119
[8.]
I. Fisher, M. Orkin.
Acquired lymphangioma (lymphangiectasis). Report of a case.
Arch Dermatol, 101 (1970), pp. 230-234
[9.]
F. Loche, H.P. Schwarze, J. Bazex.
Treatment of acquired cutaneous lymphangiectasis of the thigh and vulva with a carbon dioxide laser.
Acta Derm Venereol, 79 (1999), pp. 335
[10.]
K. Sardana, V. Mendiratta, R.C. Sharma, R.V. Koranne.
Ulcerated and nodular lesions on the vulva in a 60-year-old female.
Clin Exp Dermatol, 28 (2003), pp. 94-95
[11.]
A.V. Celis, C.N. Gaughf, O.P. Sangueza, F.W. Gourdin.
Acquired lymphangiectasis.
South Med J, 92 (1999), pp. 69-72
[12.]
M. Di Leonardo, R.A. Jacoby.
Acquired cutaneous lymphangiectasias secondary to scarring from scrofuloderma.
J Am Acad Dermatol, 14 (1986), pp. 688-690
[13.]
N.V. Heuvel, E. Stolz, A. Notowicz.
Lymphangiectases of the vulva in a patient with lymph node tuberculosis.
Int J Dermatol, 18 (1979), pp. 65-66
[14.]
B. Russell.
Lymphangioma circumscriptum and keloids.
Br J Dermatol, 63 (1951), pp. 158-159
[15.]
D.L. Tuffanelli.
Letter: lymphangiectasis due to scleroderma.
Arch Dermatol, 111 (1975), pp. 1216
[16.]
M.S. Stone.
Central-facial papular lymphangiectases: an uncommon manifestation of porphyria.
J Am Acad Dermatol, 36 (1997), pp. 493-495
[17.]
J.B. Goldstein, N.S. McNutt, G.W. Hambrick Jr., A. Hsu.
Penicillamine dermatopathy with lymphangiectases. A clinical, immunohistologic, and ultrastructural study.
Arch Dermatol, 125 (1989), pp. 92-97
[18.]
J.M. Pena, M.J. Ford.
Cutaneous lymphangiectases associated with severe photoaging and topical corticosteroid application.
J Cutan Pathol, 23 (1996), pp. 175-181
[19.]
P. Ambrojo, E.F. Cogolludo, A. Aguilar, E. Sánchez Yus, F. Sánchez de Paz.
Cutaneous lymphangiectases after therapy for carcinoma of the cervix-a case with unusual clinical and histological features.
Clin Exp Dermatol, 15 (1990), pp. 57-59
[20.]
B.P. Flanagan, E.B. Helwig.
Cutaneous lymphangioma.
Arch Dermatol, 113 (1977), pp. 24-30
[21.]
H. Kakinuma.
Occult cutaneous lymphangiectasis: an unusual case of cutaneous lymphangioma.
Acta Derm Venereol, 82 (2002), pp. 279-283
[22.]
F. el Sayed, J. Bazex, X. Bouissou, G. Laplanche, G. Samalens, G. Daste, et al.
Acquired cutaneous lymphangiectasia mimicking plantar warts.
Br J Dermatol, 132 (1995), pp. 1014-1016
[23.]
T.I. Kaya, A. Kokturk, A. Polat, U. Tursen, G. Ikizoglu.
A case of cutaneous lymphangiectasis secondary to breast cancer treatment.
Int J Dermatol, 40 (2001), pp. 760-761
[24.]
S.C. Huilgol, S. Neill, R.J. Barlow.
CO(2) laser therapy of vulval lymphangiectasia and lymphangioma circumscriptum.
Dermatol Surg, 28 (2002), pp. 575-577
[25.]
C. Novak, L. Spelman.
Low energy fluence CO2 laser treatment of lymphangiectasia.
Australas J Dermatol, 39 (1998), pp. 277-278
Copyright © 2007. Academia Española de Dermatología y Venereología and Elsevier España, S.L.
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