Topical Retinoids in the Treatment of Acne Vulgaris

Topical retinoids are highly effective in the treatment of both comedonal and inflammatory
lesions of acne and are a vital part of almost any acne regimen. A better understanding of
the structure and function of this class of medications has led to better outcomes in
treatments of patients with acne. In this article, the structure and function of retinoids is
first reviewed. Then, the clinical effectiveness and tolerability of each of the available
topical retinoid formulations is summarized.
Semin Cutan Med Surg 27:177-182 © 2008 Elsevier Inc. All rights reserved.

Topical retinoids are highly effective in the treatment of both comedonal and inflammatory
lesions of acne and are a vital part of almost any acne regimen. A better understanding of
the structure and function of this class of medications has led to better outcomes in
treatments of patients with acne. In this article, the structure and function of retinoids is
first reviewed. Then, the clinical effectiveness and tolerability of each of the available
topical retinoid formulations is summarized.
Semin Cutan Med Surg 27:177-182 © 2008 Elsevier Inc. All rights reserved.

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