Elsevier

Radiology Case Reports

Volume 13, Issue 1, February 2018, Pages 275-280
Radiology Case Reports

Oncology
Myopericytoma/myopericytomatosis of the lower extremity in two young patients: a recently designated rare soft tissue neoplasm

https://doi.org/10.1016/j.radcr.2017.10.010Get rights and content
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Abstract

Myopericytomas are rare, slow-growing benign perivascular tumors most commonly arising within the superficial subcutaneous soft tissues of the lower extremity. They represent one of several related perivascular tumors of myoid lineage with similar morphology and shared immunohistochemical profile including positive staining for smooth muscle actin. Histologically, myopericytoma exhibit concentric, perivascular proliferation of spindled myoid cells with bland elongated nuclei and associated blood vessels. A solitary well-demarcated nodule or mass is typically referred to as myopericytoma, whereas an infiltrative multinodular lesion has more recently been termed myopericytomatosis. At magnetic resonance imaging, tumors are most commonly superficial, may be well-defined (myopericytoma) or ill-defined (myopericytomatosis), and demonstrate highly vascularized, avidly enhancing soft tissue often with areas of internal hemorrhage. We report 2 cases involving the lower extremity (1 myopericytoma and 1 myopericytomatosis) occurring in young patients, focusing on the clinical, histopathologic, and radiologic characteristics of this relatively new distinct entity.

Keywords

Myopericytoma
Soft tissue mass
Lower extremity

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Competing Interests: The authors report no conflicts of interest or relevant disclosures.