Original ArticleLUMBAR: Association between Cutaneous Infantile Hemangiomas of the Lower Body and Regional Congenital Anomalies
Section snippets
Methods
Institutional review board (IRB) approval was obtained for this study, allowing for the collection of non-identifiable patient information from outside institutions. Because of the known rarity of this association, a call for unpublished cases of lumbosacral or perineal IH associated with at least 1 other regionally present, congenital anomaly was made through the Society for Pediatric Dermatology membership listserve. Specific information requested included patient's sex, a description of the
Results
Table I (available at www.jpeds.com) and Figures 3 and 4 describe the clinical features of 24 new, unpublished cases. There were 15 female and 9 male patients, resulting in a sex ratio of 1.7 to 1. The most common IH location was region B (sacral; 20/24; 83.3%), followed by regions A (lumbar; 18/24; 75%) and C (perineum/genitals; 16/24; 66.6%). Region D (lower extremity) was affected in 10 of 24 cases (41.7%). One case (case 1) had an additional retroperitoneal IH. Most patients (66%) had
Discussion
The term “segmental” or what some authors refer to as “regional” describes IHs that show linear patterning, geographic patterning, or both over a specific cutaneous territory, respecting embryologic anatomic boundaries, rather than appearing to arise from a single focal point. Segmental IHs show reproducible patterns associated with developmental segments, which arise from the neuroectoderm and later correspond to a specific region of skin and soft tissues.7 Clinically, segmental IH can
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The authors declare no conflicts of interest.