The Journal of Allergy and Clinical Immunology: In Practice
Original ArticlePrevalence of Inducible Urticaria in Patients with Chronic Spontaneous Urticaria: Associated Risk Factors
Section snippets
Study population
We performed a multicenter, prospective, descriptive study from August 2013 to December 2014. The study population came from a previously formed cohort (URTICA: Urticaria Research of Tropical Impact and Control Assessment, ClinicalTrials.gov number: NCT01940393).8 Because the aim of the study was to evaluate whether inhibition of the skin test wheal correlated with the clinical effect of antihistamines, patients with baseline inhibition of the cutaneous response to histamine (wheal <3 mm) were
General characteristics
Of 411 patients with CSU and 155 healthy subjects who agreed to participate in this study, 245 and 127, respectively, were included (Table I), with a female predominance in both groups (61% and 62%). In terms of origin, 251 participants were from Medellín and 121 were from Bogotá. Asthma was significantly more frequent in patients with CSU than in the control group (P < .05). No significant sex or age differences were observed between the CSU group and the control group (Table I). The median
Discussion
Most patients with CSU frequently associated exacerbations with several triggers.5 Nevertheless, the suspected trigger does not always induce symptoms, with the result that patients often subject themselves to unnecessary restrictions and changes in lifestyle. We observed a wide disparity between self-reporting and physical challenge test results among patients with CSU: according to self-reported data, 75.9% of patients with CSU had IU, although when the challenge test was performed, only
Acknowledgment
We thank the University of Antioquia for funding this study.
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Cited by (0)
This project was funded by the University of Antioquia.
Conflicts of interest: J. Sanchez has received consultancy and lecture fees from Novartis and Sanofi and has received travel support from Takeda and MSD. A. Celis has received travel support from Immunotek. R. Cardona has received consultancy and lecture fees from Novartis. The rest of the authors declare that they have no relevant conflicts of interest.