Atopic dermatitis and skin diseaseEczema and cardiovascular risk factors in 2 US adult population studies
Section snippets
National Health Interview Survey
The institutional review board at Northwestern University approved this study, and the protocol is consistent with the principles of the Declaration of Helsinki. We used data from the 2010 and 2012 National Health Interview Survey (NHIS), which are conducted by the National Center for Health Statistics and are the principal source of information on the health of the civilian noninstitutionalized population of the United States. The survey was administered in-person to selected households by
Determinants of eczema, diabetes, and hypertension
A total of 34,525 adults aged 18 to 85 years was included in the analysis of the 2012 NHIS. The US prevalence (95% CI) of eczema in adults was estimated to be 7.2% (6.9 to 7.6%). The prevalence of eczema was significantly associated with female sex (logistic regression; OR, 1.52; 95% CI, 1.36-1.70; P < .001) and post–high school education (OR, 1.39; 95% CI, 1.15-1.68; P < .001) but inversely associated with black race (OR, 0.79; 95% CI, 0.64-0.93; P = .01), Hispanic origin (OR, 0.73; 95% CI,
Discussion
Using 2 US population–based cohorts, we found that adults with eczema had higher rates of cigarette smoking and consumption of alcoholic beverages, lower rates of vigorous activity, and higher prevalence of class II/III obesity, hypertension, prediabetes, diabetes, and high cholesterol. These results could have major clinical and public health ramifications because smoking, alcohol intake, and sedentary lifestyle are all modifiable risk factors. Patients with AD may be candidates for aggressive
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Disclosure of potential conflict of interest: The authors declare that they have no relevant conflicts of interest.