Original articleSuperficial x-ray in the treatment of basal and squamous cell carcinomas: A viable option in select patients
Section snippets
Methods
Using records obtained from Dermatology Associates of Tallahassee in Florida, a retrospective analysis was performed on 1715 histologically confirmed primary, nonaggressive cutaneous BCC and SCC treated with SXRT between 2000 and 2010 in this practice. Pertinent clinical information regarding the tumor characteristics was recorded including anatomic location, lesion diameter, histologic morphology, and evidence of recurrence at follow-up. Initial and recurrent carcinomas were staged according
Results
A total of 1715 tumors in 1149 patients were treated with SXRT from 2000 and 2010 at our practice. Of the 1715 tumors reviewed during this period, 712 were histologically proven BCC (631 nodular and 81 superficial), 994 were SCC (861 SCC in situ and 133 invasive SCC), and 9 displayed distinct features of both BCC and SCC in same biopsy specimen. The locations of the tumors are listed in Table I and the tumor types and recurrences are listed in Table II. The male-to-female ratio was 2:1. The
Discussion
Of the 1715 primary lesions treated with SXRT in our study, 45 were considered to be recurrent at follow-up. The raw recurrence rate for all tumors treated was 2.6%. Because of the variation in follow-up lengths among patients, Kaplan-Meier estimates were used to estimate the control rates for all tumors at 2- and 5-year intervals and were found to be 98.1% and 95.0%, respectively. These numbers are conservative for a number of reasons. Any tumor in the study that arose within or contiguous to
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Funding sources: None.
Disclosure: Dr Cognetta has served as a medical advisor for Topex (Now Sensus Healthcare), has served as an advisor for Sensus Health Care, was given a stock option by Sensus Healthcare for his advisory role during the company’s early stages, and was an initial investor in the company. Mr Howard, Mr Heaton, and Drs Stoddard, Hong, and Green have no conflicts of interest to declare.