Case reportA case of syringotropic cutaneous T-cell lymphoma treated with local radiotherapy
Section snippets
Discussion
Patients with SCTCL characteristically present with punctuate erythematous or hypopigmented plaques. Alopecia, hypoesthesia, and anhydrosis are variably associated with this condition.1, 2 Occasionally, SCTCL presents with erythroderma, skin nodules or lymphadenopathy mimicking scleroderma, or Sézary syndrome.3, 4 It is reported that SCTCL could occur at sites of actinic exposure, theorizing that the relative depletion of Langerhan cells caused by sun damage could curtail immune surveillance
Conclusion
Our experience confirms the excellent outcome in early stage SCTCL with local radiotherapy. While it is difficult to make broad therapeutic recommendations based on a single case report, we believe that it may be possible to reserve systemic therapy for more advanced stages of the disease. In addition to irradiating early lesions, we recommend close follow-up after treatment with periodic skin checks and early intervention if required.
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Cited by (11)
[Translated article] Treatment-Resistant Acral Papules
2022, Actas Dermo-SifiliograficasSyringotropic mycosis fungoides: Clinical and histologic features, response to treatment, and outcome in 19 patients
2014, Journal of the American Academy of DermatologySyringotropic cutaneous T-cell lymphoma mimicking dermatomycosis
2012, Annales de Dermatologie et de Venereologie
Funding sources: None.
Conflicts of interest: None declared.