Dermatologic SurgeryBasal cell carcinoma treated with Mohs surgery in Australia II. Outcome at 5-year follow-up
Section snippets
Method
We conducted a prospective, noncomparative, multicenter, interventional case series of patients with cutaneous BCC treated with MMS in Australia and monitored by the Skin and Cancer Foundation Australia between 1993 and 2002.
All patients were treated by fellowship-trained Mohs surgeons using standard fresh-frozen MMS techniques. The general technique was based on constructing a tissue map followed by color coding of the excised tissue. Frozen sections of the entire outer margin in a continuous
Patients with 5-year follow-up
Three thousand three hundred seventy (3370) patients (1594 female and 1776 male patients) completed a 5-year follow-up period after MMS. The mean age (± standard error of the mean) of these patients was 61 ± 14 years (median, 62; range, 17-92 years). In 1886 patients (56.0%) the lesion was a primary tumor, and in 1484 patients (44.0%) the lesion was a recurrent tumor (previously treated with non-Mohs procedures).
The most common stated reasons for patient referral for MMS in patients with 5-year
Discussion
The increase in the worldwide incidence of BCC has resulted in many studies that have evaluated different surgical and nonsurgical treatment modalities.2, 3 The choice of treatment options is based on multiple variables, such as patient factors (age, sex, general health), tumor characteristics (size, location, histologic subtype), as well as the treating physician's preference and available resources.2, 3
Nonsurgical treatments commonly used for BCC include cryotherapy, radiation therapy, and
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