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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction and objectives</span><p class="elsevierStyleSimplePara elsevierViewall">Microcystic adnexal carcinoma is a rare and aggressive tumor that manifests clinically as a subcutaneous nodule located on the head or neck&#46; The tumor can be confused clinically and histologically with other benign and malignant skin lesions&#44; often leading to inappropriate initial treatment&#46; The chief concern with microcystic adnexal carcinoma is the elevated morbidity and the high rate of recurrence after wide local excision&#46; Recent preliminary studies point to higher cure rates with Mohs micrographic surgery&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We reviewed the medical histories of 6 consecutive patients with microcystic adnexal carcinoma who underwent Mohs micrographic surgery in our dermatology department between 1995 and 2007&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">In all cases&#44; lesions were located on the head and were primary tumors&#46; Seventy percent of the tumors were wrongly diagnosed initially as basal cell carcinoma&#46; Perineural invasion was not detected in any patient&#44; and all were free of recurrence after between 1 and 12 years of postoperative follow-up&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The absence of perineural involvement and substantial cell atypia can be attributed to the lesions being primary tumors&#46; This would provide a rationale for definitive radical treatment of the primary tumor from the outset to avoid the complications associated with recurrence&#46; The site and the absence of recurrence in all our patients who underwent Mohs micrographic surgery support the use of this technique as the treatment of choice in microcystic adnexal carcinoma&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n y objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">El carcinoma anexial microqu&#237;stico &#40;CAM&#41; es un tumor raro y agresivo que cl&#237;nicamente se manifiesta como un n&#243;dulo subcut&#225;neo localizado en las regiones de cabeza y cuello&#46; Esta tumoraci&#243;n puede ser cl&#237;nica e histol&#243;gicamente confundida con otras lesiones cut&#225;neas benignas o malignas&#44; loque con frecuencia conduce a un tratamiento inicial err&#243;neo&#46; La principal complicaci&#243;n del CAM es la alta morbilidad y la elevada tasa de recurrencia tras escisi&#243;n local amplia&#46; Estudios preliminares recientes han mostrado unas mayores tasas de curaci&#243;n mediante cirug&#237;a microgr&#225;fica de Mohs &#40;CMM&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se revisaron las historias cl&#237;nicas de 6 pacientes consecutivos con CAM tratados mediante CMM en nuestro Servicio de Dermatolog&#237;a entre 1995 y 2007&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Todos los casos se localizaron en la cabeza y el 100&#37; fue tumor primario&#46; En el 70&#37; de los casos el tumor fue inicialmente mal diagnosticado de carcinoma basocelular&#46; No se detect&#243; invasi&#243;n perineural en ninguno de los casos y la recurrencia estuvo ausente en todos los pacientes tras un periodo de seguimiento comprendido entre 1 y 12 a&#241;os posteriores a la CMM&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La ausencia de afectaci&#243;n perineural y de una importante atipia celular puede deberse al car&#225;cter primario de la tumoraci&#243;n&#46; Ello justificar&#237;a la necesidad de un tratamiento definitivo radical inicial del tumor primario para evitar las complicaciones que implica una recidiva tumoral&#46; La localizaci&#243;n y la ausencia de recurrencia en todos nuestros casos tratados mediante CMM apoyan el uso de esta t&#233;cnica como el tratamiento de elecci&#243;n para el CAM&#46;</p>"
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Original articles
Microcystic Adnexal Carcinoma: Mohs Micrographic Surgery as the Treatment of Choice
Carcinoma Anexial Microquístico : la Cirugía Micrográfica de Mohs Como Tratamiento de Elección
A. Martorell-Calatayuda,
Corresponding author
antmarto@hotmail.com

Correspondence: Antonio Martorell Calatayud, C/ San José de la Montaña, 14, puerta 11, 46008 Valencia, Spain.
, C. Requena-Caballeroa, R. Botella-Estradaa, S. Almenar-Medinab, O. Sanmartín-Jiméneza, B. Llombart-Cussaca, E. Nagore-Enguídanosa, C. Serra-Guilléna, B. Echeverría-Garcíaa, C. Guillén-Baronaa
a Servicio de Dermatología, Instituto Valenciano de Oncología, Valencia, Spain
b Servicio de Anatomía Patológica, Instituto Valenciano de Oncología, Valencia, Spain
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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction and objectives</span><p class="elsevierStyleSimplePara elsevierViewall">Microcystic adnexal carcinoma is a rare and aggressive tumor that manifests clinically as a subcutaneous nodule located on the head or neck&#46; The tumor can be confused clinically and histologically with other benign and malignant skin lesions&#44; often leading to inappropriate initial treatment&#46; The chief concern with microcystic adnexal carcinoma is the elevated morbidity and the high rate of recurrence after wide local excision&#46; Recent preliminary studies point to higher cure rates with Mohs micrographic surgery&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We reviewed the medical histories of 6 consecutive patients with microcystic adnexal carcinoma who underwent Mohs micrographic surgery in our dermatology department between 1995 and 2007&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">In all cases&#44; lesions were located on the head and were primary tumors&#46; Seventy percent of the tumors were wrongly diagnosed initially as basal cell carcinoma&#46; Perineural invasion was not detected in any patient&#44; and all were free of recurrence after between 1 and 12 years of postoperative follow-up&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The absence of perineural involvement and substantial cell atypia can be attributed to the lesions being primary tumors&#46; This would provide a rationale for definitive radical treatment of the primary tumor from the outset to avoid the complications associated with recurrence&#46; The site and the absence of recurrence in all our patients who underwent Mohs micrographic surgery support the use of this technique as the treatment of choice in microcystic adnexal carcinoma&#46;</p>"
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        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n y objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">El carcinoma anexial microqu&#237;stico &#40;CAM&#41; es un tumor raro y agresivo que cl&#237;nicamente se manifiesta como un n&#243;dulo subcut&#225;neo localizado en las regiones de cabeza y cuello&#46; Esta tumoraci&#243;n puede ser cl&#237;nica e histol&#243;gicamente confundida con otras lesiones cut&#225;neas benignas o malignas&#44; loque con frecuencia conduce a un tratamiento inicial err&#243;neo&#46; La principal complicaci&#243;n del CAM es la alta morbilidad y la elevada tasa de recurrencia tras escisi&#243;n local amplia&#46; Estudios preliminares recientes han mostrado unas mayores tasas de curaci&#243;n mediante cirug&#237;a microgr&#225;fica de Mohs &#40;CMM&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se revisaron las historias cl&#237;nicas de 6 pacientes consecutivos con CAM tratados mediante CMM en nuestro Servicio de Dermatolog&#237;a entre 1995 y 2007&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Todos los casos se localizaron en la cabeza y el 100&#37; fue tumor primario&#46; En el 70&#37; de los casos el tumor fue inicialmente mal diagnosticado de carcinoma basocelular&#46; No se detect&#243; invasi&#243;n perineural en ninguno de los casos y la recurrencia estuvo ausente en todos los pacientes tras un periodo de seguimiento comprendido entre 1 y 12 a&#241;os posteriores a la CMM&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La ausencia de afectaci&#243;n perineural y de una importante atipia celular puede deberse al car&#225;cter primario de la tumoraci&#243;n&#46; Ello justificar&#237;a la necesidad de un tratamiento definitivo radical inicial del tumor primario para evitar las complicaciones que implica una recidiva tumoral&#46; La localizaci&#243;n y la ausencia de recurrencia en todos nuestros casos tratados mediante CMM apoyan el uso de esta t&#233;cnica como el tratamiento de elecci&#243;n para el CAM&#46;</p>"
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Article information
ISSN: 15782190
Original language: English
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