Correspondence: Antonio Martorell Calatayud, C/ San José de la Montaña, 14, puerta 11, 46008 Valencia, Spain.
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"apellidos" => "Giménez-Arnau" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009701507?idApp=UINPBA000044" "url" => "/15782190/0000010000000008/v1_201304241504/S1578219009701507/v1_201304241504/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original articles</span>" "titulo" => "Microcystic Adnexal Carcinoma: Mohs Micrographic Surgery as the Treatment of Choice" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "693" "paginaFinal" => "699" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "A. Martorell-Calatayud, C. Requena-Caballero, R. Botella-Estrada, S. Almenar-Medina, O. Sanmartín-Jiménez, B. Llombart-Cussac, E. Nagore-Enguídanos, C. Serra-Guillén, B. Echeverría-García, C. Guillén-Barona" "autores" => array:10 [ 0 => array:4 [ "nombre" => "A." "apellidos" => "Martorell-Calatayud" "email" => array:1 [ 0 => "antmarto@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "C." "apellidos" => "Requena-Caballero" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 2 => array:3 [ "nombre" => "R." "apellidos" => "Botella-Estrada" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 3 => array:3 [ "nombre" => "S." "apellidos" => "Almenar-Medina" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 4 => array:3 [ "nombre" => "O." "apellidos" => "Sanmartín-Jiménez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 5 => array:3 [ "nombre" => "B." "apellidos" => "Llombart-Cussac" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 6 => array:3 [ "nombre" => "E." "apellidos" => "Nagore-Enguídanos" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 7 => array:3 [ "nombre" => "C." "apellidos" => "Serra-Guillén" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 8 => array:3 [ "nombre" => "B." "apellidos" => "Echeverría-García" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 9 => array:3 [ "nombre" => "C." "apellidos" => "Guillén-Barona" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Instituto Valenciano de Oncología, Valencia, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Instituto Valenciano de Oncología, Valencia, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondence: Antonio Martorell Calatayud, C/ San José de la Montaña, 14, puerta 11, 46008 Valencia, Spain." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Carcinoma Anexial Microquístico : la Cirugía Micrográfica de Mohs Como Tratamiento de Elección" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2009-01-16" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec84578" "palabras" => array:3 [ 0 => "microcystic adnexal carcinoma" 1 => "Mohs surgery" 2 => "perineural invasion" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84577" "palabras" => array:3 [ 0 => "carcinoma anexial microquístico" 1 => "cirugía de Mohs" 2 => "invasión perineural" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction and objectives</span><p class="elsevierStyleSimplePara elsevierViewall">Microcystic adnexal carcinoma is a rare and aggressive tumor that manifests clinically as a subcutaneous nodule located on the head or neck. The tumor can be confused clinically and histologically with other benign and malignant skin lesions, often leading to inappropriate initial treatment. The chief concern with microcystic adnexal carcinoma is the elevated morbidity and the high rate of recurrence after wide local excision. Recent preliminary studies point to higher cure rates with Mohs micrographic surgery.</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We reviewed the medical histories of 6 consecutive patients with microcystic adnexal carcinoma who underwent Mohs micrographic surgery in our dermatology department between 1995 and 2007.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">In all cases, lesions were located on the head and were primary tumors. Seventy percent of the tumors were wrongly diagnosed initially as basal cell carcinoma. Perineural invasion was not detected in any patient, and all were free of recurrence after between 1 and 12 years of postoperative follow-up.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The absence of perineural involvement and substantial cell atypia can be attributed to the lesions being primary tumors. This would provide a rationale for definitive radical treatment of the primary tumor from the outset to avoid the complications associated with recurrence. The site and the absence of recurrence in all our patients who underwent Mohs micrographic surgery support the use of this technique as the treatment of choice in microcystic adnexal carcinoma.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción y objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">El carcinoma anexial microquístico (CAM) es un tumor raro y agresivo que clínicamente se manifiesta como un nódulo subcutáneo localizado en las regiones de cabeza y cuello. Esta tumoración puede ser clínica e histológicamente confundida con otras lesiones cutáneas benignas o malignas, loque con frecuencia conduce a un tratamiento inicial erróneo. La principal complicación del CAM es la alta morbilidad y la elevada tasa de recurrencia tras escisión local amplia. Estudios preliminares recientes han mostrado unas mayores tasas de curación mediante cirugía micrográfica de Mohs (CMM).</p> <span class="elsevierStyleSectionTitle">Material y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se revisaron las historias clínicas de 6 pacientes consecutivos con CAM tratados mediante CMM en nuestro Servicio de Dermatología entre 1995 y 2007.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Todos los casos se localizaron en la cabeza y el 100% fue tumor primario. En el 70% de los casos el tumor fue inicialmente mal diagnosticado de carcinoma basocelular. No se detectó invasión perineural en ninguno de los casos y la recurrencia estuvo ausente en todos los pacientes tras un periodo de seguimiento comprendido entre 1 y 12 años posteriores a la CMM.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La ausencia de afectación perineural y de una importante atipia celular puede deberse al carácter primario de la tumoración. Ello justificaría la necesidad de un tratamiento definitivo radical inicial del tumor primario para evitar las complicaciones que implica una recidiva tumoral. La localización y la ausencia de recurrencia en todos nuestros casos tratados mediante CMM apoyan el uso de esta técnica como el tratamiento de elección para el CAM.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:54 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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Year/Month | Html | Total | |
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2024 October | 33 | 35 | 68 |
2024 September | 57 | 69 | 126 |
2024 August | 112 | 106 | 218 |
2024 July | 81 | 81 | 162 |
2024 June | 71 | 105 | 176 |
2024 May | 84 | 78 | 162 |
2024 April | 81 | 68 | 149 |
2024 March | 66 | 81 | 147 |
2024 February | 40 | 58 | 98 |
2024 January | 45 | 76 | 121 |
2023 December | 51 | 77 | 128 |
2023 November | 63 | 82 | 145 |
2023 October | 66 | 81 | 147 |
2023 September | 45 | 76 | 121 |
2023 August | 25 | 82 | 107 |
2023 July | 52 | 74 | 126 |
2023 June | 39 | 69 | 108 |
2023 May | 38 | 82 | 120 |
2023 April | 35 | 63 | 98 |
2023 March | 22 | 54 | 76 |
2023 February | 28 | 49 | 77 |
2023 January | 23 | 62 | 85 |
2022 December | 39 | 69 | 108 |
2022 November | 20 | 56 | 76 |
2022 October | 19 | 43 | 62 |
2022 September | 18 | 71 | 89 |
2022 August | 16 | 72 | 88 |
2022 July | 17 | 41 | 58 |
2022 June | 9 | 27 | 36 |
2022 May | 31 | 79 | 110 |
2022 April | 35 | 60 | 95 |
2022 March | 21 | 86 | 107 |
2022 February | 20 | 47 | 67 |
2022 January | 22 | 66 | 88 |
2021 December | 16 | 56 | 72 |
2021 November | 37 | 67 | 104 |
2021 October | 28 | 65 | 93 |
2021 September | 28 | 68 | 96 |
2021 August | 24 | 33 | 57 |
2021 July | 24 | 51 | 75 |
2021 June | 24 | 46 | 70 |
2021 May | 19 | 37 | 56 |
2021 April | 46 | 71 | 117 |
2021 March | 69 | 33 | 102 |
2021 February | 66 | 45 | 111 |
2021 January | 40 | 36 | 76 |
2020 December | 21 | 30 | 51 |
2020 November | 23 | 32 | 55 |
2020 October | 16 | 25 | 41 |
2020 September | 16 | 22 | 38 |
2020 August | 17 | 27 | 44 |
2020 July | 13 | 14 | 27 |
2020 June | 25 | 25 | 50 |
2020 May | 13 | 28 | 41 |
2020 April | 13 | 23 | 36 |
2020 March | 19 | 19 | 38 |
2020 February | 1 | 7 | 8 |
2020 January | 0 | 23 | 23 |
2019 December | 0 | 16 | 16 |
2019 November | 0 | 19 | 19 |
2019 October | 0 | 28 | 28 |
2019 September | 0 | 29 | 29 |
2019 August | 0 | 14 | 14 |
2019 July | 0 | 30 | 30 |
2019 June | 0 | 12 | 12 |
2019 May | 1 | 68 | 69 |
2019 April | 0 | 33 | 33 |
2019 March | 0 | 4 | 4 |
2019 February | 0 | 8 | 8 |
2019 January | 0 | 2 | 2 |
2018 December | 0 | 10 | 10 |
2018 September | 0 | 3 | 3 |
2018 August | 0 | 1 | 1 |
2018 June | 0 | 2 | 2 |
2018 April | 0 | 1 | 1 |
2018 February | 14 | 10 | 24 |
2018 January | 20 | 7 | 27 |
2017 December | 18 | 13 | 31 |
2017 November | 19 | 7 | 26 |
2017 October | 14 | 19 | 33 |
2017 September | 11 | 12 | 23 |
2017 August | 18 | 18 | 36 |
2017 July | 17 | 13 | 30 |
2017 June | 26 | 29 | 55 |
2017 May | 26 | 15 | 41 |
2017 April | 17 | 14 | 31 |
2017 March | 16 | 42 | 58 |
2017 February | 18 | 27 | 45 |
2017 January | 15 | 24 | 39 |
2016 December | 33 | 17 | 50 |
2016 November | 27 | 21 | 48 |
2016 October | 22 | 23 | 45 |
2016 September | 30 | 21 | 51 |
2016 August | 30 | 18 | 48 |
2016 July | 29 | 8 | 37 |
2016 June | 8 | 8 | 16 |
2016 May | 7 | 9 | 16 |
2016 April | 5 | 12 | 17 |
2016 March | 1 | 15 | 16 |
2016 February | 8 | 11 | 19 |
2016 January | 6 | 12 | 18 |
2015 December | 12 | 5 | 17 |
2015 November | 11 | 11 | 22 |
2015 October | 14 | 13 | 27 |
2015 September | 5 | 3 | 8 |
2015 August | 8 | 3 | 11 |
2015 July | 29 | 15 | 44 |
2015 June | 26 | 23 | 49 |
2015 May | 61 | 29 | 90 |
2015 April | 36 | 29 | 65 |
2015 March | 26 | 22 | 48 |
2015 February | 20 | 24 | 44 |
2015 January | 22 | 23 | 45 |
2014 December | 35 | 26 | 61 |
2014 November | 27 | 30 | 57 |
2014 October | 39 | 34 | 73 |
2014 September | 45 | 27 | 72 |
2014 August | 49 | 25 | 74 |
2014 July | 55 | 27 | 82 |
2014 June | 38 | 10 | 48 |
2014 May | 43 | 25 | 68 |
2014 April | 51 | 7 | 58 |
2014 March | 47 | 31 | 78 |
2014 February | 42 | 32 | 74 |
2014 January | 24 | 32 | 56 |
2013 December | 29 | 24 | 53 |
2013 November | 25 | 29 | 54 |
2013 October | 39 | 26 | 65 |
2013 September | 36 | 28 | 64 |
2013 August | 31 | 37 | 68 |
2013 July | 29 | 54 | 83 |
2013 June | 30 | 49 | 79 |
2013 May | 29 | 38 | 67 |
2013 April | 33 | 31 | 64 |
2013 March | 38 | 29 | 67 |
2013 February | 41 | 13 | 54 |
2013 January | 7 | 3 | 10 |