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        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">Hidradenitis suppurativa is a chronic inflammatory disease that runs in outbreaks with painful lesions&#44; fistulas and scars in axillae&#44; groins&#44; buttocks&#44; and perianal and submammary regions&#46; Among multiple drug therapies available&#44; infliximab&#44; usually employed in dermatology to control psoriasis&#44; has shown its efficacy in the past five years&#46;</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p class="elsevierStyleSimplePara elsevierViewall">It is a prospective&#44; observational study to determine the efficacy and safety of infliximab in the treatment of hidradenitis suppurativa&#46; We selected three women with a history of hidradenitis suppurativa of more than 10 years&#44; with involvement of at least two anatomic locations that was recalcitrant to conventional therapies&#46; Each patient received infliximab at a dose of 5<span class="elsevierStyleHsp" style=""></span>mg&#47;kg&#47;infusion on weeks 0&#44; 2&#44; 6 and every 8 weeks thereafter&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Two of the three patients showed mild to moderate improvement of their disease while the third patient did not improve&#46; We can highlight the variability of the results observed in these three patients&#46; Adverse effects were generally mild and well tolerated by the three patients&#46; Despite this&#44; two patients withdrew the therapy due to loss of efficacy in one case and the development of generalized arthalgias in the other case&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Treatment of hidradenitis supurativa with infliximab constitutes a moderately useful alternative in some cases&#46;</p>"
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Hidradenitis Suppurativa. Response to Treatment With Infliximab
Hidrosadenitis Supurativa. Respuesta al Tratamiento con Infliximab
J. Pedraz
Corresponding author
javierpedraz@aedv.es

Correspondence: Servicio de Dermatología, Hospital Universitario de la Princesa. Diego de León, 62. 28006 Madrid. Spain.
, E. Daudén, S. Pérez-Gala, R. Goiriz-Valdés, P. Fernández-Peñas, A. García-Diez
Servicio de Dermatología, Hospital Universitario de la Princesa, Madrid, Spain
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">Hidradenitis suppurativa is a chronic inflammatory disease that runs in outbreaks with painful lesions&#44; fistulas and scars in axillae&#44; groins&#44; buttocks&#44; and perianal and submammary regions&#46; Among multiple drug therapies available&#44; infliximab&#44; usually employed in dermatology to control psoriasis&#44; has shown its efficacy in the past five years&#46;</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p class="elsevierStyleSimplePara elsevierViewall">It is a prospective&#44; observational study to determine the efficacy and safety of infliximab in the treatment of hidradenitis suppurativa&#46; We selected three women with a history of hidradenitis suppurativa of more than 10 years&#44; with involvement of at least two anatomic locations that was recalcitrant to conventional therapies&#46; Each patient received infliximab at a dose of 5<span class="elsevierStyleHsp" style=""></span>mg&#47;kg&#47;infusion on weeks 0&#44; 2&#44; 6 and every 8 weeks thereafter&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Two of the three patients showed mild to moderate improvement of their disease while the third patient did not improve&#46; We can highlight the variability of the results observed in these three patients&#46; Adverse effects were generally mild and well tolerated by the three patients&#46; Despite this&#44; two patients withdrew the therapy due to loss of efficacy in one case and the development of generalized arthalgias in the other case&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Treatment of hidradenitis supurativa with infliximab constitutes a moderately useful alternative in some cases&#46;</p>"
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ISSN: 15782190
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